MicroRNA Childhood Cancer Catalog (M3Cs)

Publication Title	DOI	Year
HMGA2 as a potential molecular target in KMT2A-AFF1-positive infant acute lymphoblastic leukaemia.	https://doi.org/10.1111/bjh.13763	2015	Cell line 0 Master/Detail View	Cell line and drug 2 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies.	https://doi.org/10.1038/leu.2014.302	2015	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Effects of microRNA-21 on the biological functions of T-cell acute lymphoblastic lymphoma/leukemia	https://doi.org/10.3892/ol.2016.5163	2016	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Bone Marrow Microenvironment Niche Regulates miR-221/222 in Acute Lymphoblastic Leukemia.	https://doi.org/10.1158/1541-7786.MCR-15-0474	2016	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia jurkat cells by modulating expression of fas-associated protein with death domain (FADD).	https://doi.org/10.1016/j.bbamcr.2013.11.022	2014	Cell line 0 Master/Detail View	Cell line and drug 2 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Expression of the miR-150 tumor suppressor is restored by and synergizes with rapamycin in a human leukemia T-cell line.	https://doi.org/10.1016/j.leukres.2018.09.009	2018	Cell line 1 Master/Detail View	Cell line and drug 3 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Involvement of miR17 pathway in glucocorticoid-induced cell death in pediatric acute lymphoblastic leukemia	https://doi.org/10.3109/10428194.2012.678004	2012	Cell line 1 Master/Detail View	Cell line and drug 2 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Glucocorticoid-regulated microRNAs and mirtrons in acute lymphoblastic leukemia.	https://doi.org/10.1038/leu.2008.370	2009	Cell line 0 Master/Detail View	Cell line and drug 12 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47.	https://doi.org/10.1186/s12943-018-0768-2	2018	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Interleukin-23 acts as antitumor agent on childhood B-acute lymphoblastic leukemia cells.	https://doi.org/10.1182/blood-2009-10-248245	2010	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
The regulatory ZFAS1/miR-150/ST6GAL1 crosstalk modulates sialylation of EGFR via PI3K/Akt pathway in T-cell acute lymphoblastic leukemia.	https://doi.org/10.1186/s13046-019-1208-x	2019	Cell line 4 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Loss of miR-146b-5p promotes T cell acute lymphoblastic leukemia migration and invasion via the IL-17A pathway.	https://doi.org/10.1002/jcb.27882	2018	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA 181a influences the expression of HMGB1 and CD4 in acute Leukemias.	https://doi.org/1791-7530 (Electronic)	2013	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
microRNA-181a enhances cell proliferation in acute lymphoblastic leukemia by targeting EGR1.	https://doi.org/10.1016/j.leukres.2015.01.010	2015	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20.	https://doi.org/10.18632/oncotarget.12018	2016	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221.	https://doi.org/10.1182/blood-2008-12-191619	2009	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemia.	https://doi.org/10.1038/srep31894	2016	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia.	https://doi.org/10.1016/j.leukres.2015.11.016	2015	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Potential roles of microRNA-29a in the molecular pathophysiology of T-cell acute lymphoblastic leukemia.	https://doi.org/10.1111/cas.12766	2015	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Integrating microRNA and mRNA expression in rapamycin-treated T-cell acute lymphoblastic leukemia.	https://doi.org/10.1016/j.prp.2019.152494	2019	Cell line 0 Master/Detail View	Cell line and drug 9 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View

Publications