MicroRNA Childhood Cancer Catalog (M3Cs)

Publication Title	DOI	Year
Dysregulated circRNA_100876 suppresses proliferation of osteosarcoma cancer cells by targeting microRNA-136	https://doi.org/10.1002/jcb.28837	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Fibronectin-1 modulated by the long noncoding RNA OIP5-AS1/miR-200b-3p axis contributes to doxorubicin resistance of osteosarcoma cells	https://doi.org/10.1002/jcp.27435	2019	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Long noncoding RNA APTR contributes to osteosarcoma progression through repression of miR-132-3p and upregulation of yes-associated protein 1	https://doi.org/10.1002/jcp.27572	2019	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Loss of MicroRNA-489-3p promotes osteosarcoma metastasis by activating PAX3-MET pathway	https://doi.org/10.1002/mc.22593	2017	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Long noncoding RNA NEAT1 regulates the development of osteosarcoma through sponging miR-34a-5p to mediate HOXA13 expression as a competitive endogenous RNA	https://doi.org/10.1002/mgg3.673	2019	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
LncRNA SNHG16 sponges miR-98-5p to regulate cellular processes in osteosarcoma	https://doi.org/10.1007/s00280-019-03822-5	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
A novel interplay between HOTAIR and DNA methylation in osteosarcoma cells indicates a new therapeutic strategy	2017	2017	Cell line 0 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Effect of microRNA-101 on proliferation and apoptosis of human osteosarcoma cells by targeting mTOR	https://doi.org/10.1007/s11596-014-1369-y	2014	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-100 inhibits osteosarcoma cell proliferation by targeting Cyr61	https://doi.org/10.1007/s13277-013-1146-8	2014	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MiR-145 inhibits osteosarcoma cells proliferation and invasion by targeting ROCK1	https://doi.org/10.1007/s13277-014-2031-9	2014	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Notch-mediated repression of miR-223 contributes to IGF1R regulation in T-ALL.	https://doi.org/10.1016/j.leukres.2012.02.013	2012	Cell line 2 Master/Detail View	Cell line and drug 5 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Regulation of RAB5C is important for the growth inhibitory effects of MiR-509 in human precursor-B acute lymphoblastic leukemia.	https://doi.org/10.1371/journal.pone.0111777	2014	Cell line 4 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150.	https://doi.org/10.1182/blood-2010-12-326629	2011	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia.	https://doi.org/10.1038/leu.2014.133	2014	Cell line 1 Master/Detail View	Cell line and drug 2 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia.	https://doi.org/10.1084/jem.20122516	2013	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a.	https://doi.org/10.1182/blood-2009-02-206706	2010	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD.	https://doi.org/10.1038/leu.2017.80	2017	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by down-regulating ERK BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression	https://doi.org/10.1038/leu.2017.82	2017	Cell line 0 Master/Detail View	Cell line and drug 10 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukem	https://doi.org/10.1186/1756-8722-6-21	2013	Cell line 0 Master/Detail View	Cell line and drug 3 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia	https://doi.org/10.1002/jcp.28294	2019	Cell line 0 Master/Detail View	Cell line and drug 3 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View

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