MicroRNA Childhood Cancer Catalog (M3Cs)

Publication Title	DOI	Year
miR-22 inhibits osteosarcoma cell proliferation and migration by targeting HMGB1 and inhibiting HMGB1-mediated autophagy	https://doi.org/10.1007/s13277-014-1965-2	2014	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-335 negatively regulates osteosarcoma stem cell-like properties by targeting POU5F1	https://doi.org/10.1186/s12935-017-0398-6	2017	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-363 acts as a tumor suppressor in osteosarcoma cells by inhibiting PDZD2	https://doi.org/10.3892/or.2019.7078	2019	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expression	https://doi.org/10.1158/0008-5472.CAN-11-1460	2012	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity	https://doi.org/10.1158/1541-7786.MCR-13-0292	2013	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Tumor-suppressive microRNA-let-7a inhibits cell proliferation via targeting of E2F2 in osteosarcoma cells	https://doi.org/10.3892/ijo.2015.2867	2015	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miRNA-193a-5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors	https://doi.org/10.18632/oncotarget.10950	2016	Cell line 6 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Overexpression of miR-126 sensitizes osteosarcoma cells to apoptosis induced by epigallocatechin-3-gallate	https://doi.org/10.1186/1477-7819-12-383	2014	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
p16INK4a inhibits the proliferation of osteosarcoma cells through regulating the miR-146b-5p/TRAF6 pathway	https://doi.org/10.1042/BSR20181268	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Overexpression of microRNA-448 inhibits osteosarcoma cell proliferation and invasion through targeting of astrocyte elevated gene-1	https://doi.org/10.3892/mmr.2017.7249	2017	Cell line 4 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells	https://doi.org/10.1186/s13046-015-0192-z	2015	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MiR-199a-3p affects the multi-chemoresistance of osteosarcoma through targeting AK4	https://doi.org/10.1186/s12885-018-4460-0	2018	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-15a represses cancer cell migration and invasion under conditions of hypoxia by targeting and downregulating Bcl-2 expression in human osteosarcoma cells	https://doi.org/10.3892/ijo.2018.4285	2018	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Upregulation of long non-coding RNA NNT-AS1 promotes osteosarcoma progression by inhibiting the tumor suppressive miR-320a	https://doi.org/10.1080/15384047.2018.1538612	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
H19 Functions as a ceRNA in Promoting Metastasis Through Decreasing miR-200s Activity in Osteosarcoma	https://doi.org/10.1089/dna.2015.3171	2016	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-34a increases cisplatin sensitivity of osteosarcoma cells in vitro through up-regulation of c-Myc and Bim signal	https://doi.org/10.3233/CBM-170452	2017	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MiR-374a Activates Wnt/?-Catenin Signaling to Promote Osteosarcoma Cell Migration by Targeting WIF-1	https://doi.org/10.1007/s12253-018-0556-8	2018	Cell line 4 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Circ_ORC2 enhances the regulatory effect of miR-19a on its target gene PTEN to affect osteosarcoma cell growth	https://doi.org/10.1016/j.bbrc.2019.04.188	2019	Cell line 5 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-22 targets the 3' UTR of HMGB1 and inhibits the HMGB1-associated autophagy in osteosarcoma cells during chemotherapy	https://doi.org/10.1007/s13277-014-1797-0	2014	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells	https://doi.org/10.1155/2019/7028901	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View

Publications