MicroRNA Childhood Cancer Catalog (M3Cs)

Publication Title	DOI	Year
MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression	https://doi.org/10.1038/mt.2011.53	2011	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Post-translational regulation contributes to the loss of LKB1 expression through SIRT1 deacetylase in osteosarcomas	https://doi.org/10.1038/bjc.2017.174	2017	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Upregulation of circular RNA circ_0000502 predicts unfavorable prognosis in osteosarcoma and facilitates cell progression via sponging miR-1238	https://doi.org/10.1002/jcb.28134	2018	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Up-regulation of microRNA-496 suppresses proliferation, invasion, migration and in vivo tumorigenicity of human osteosarcoma cells by targeting eIF4E	https://doi.org/10.1016/j.biochi.2019.04.017	2019	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-493 inhibits the proliferation and invasion of osteosarcoma cells through directly targeting specificity protein 1	https://doi.org/10.3892/ol.2018.8268	2018	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-493 inhibits the proliferation and invasion of osteosarcoma cells through directly targeting specificity protein 1	https://doi.org/10.3892/ol.2018.8268	2018	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-488 inhibits proliferation, invasion and EMT in osteosarcoma cell lines by targeting aquaporin 3	https://doi.org/10.3892/ijo.2018.4483	2018	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Pivotal role of microRNA-9 in osteosarcoma tumorigenesis and tumor progression	https://doi.org/10.4238/gmr.15017318	2016	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-26a induces osteosarcoma cell growth and metastasis via the Wnt/?-catenin pathway	https://doi.org/10.3892/ol.2015.4073	2016	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-214 functions as an oncogene in human osteosarcoma by targeting TRAF3	https://doi.org/10.26355/eurrev_201808_15711	2018	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
The circular RNA circ-ITCH acts as a tumour suppressor in osteosarcoma via regulating miR-22	https://doi.org/10.1080/21691401.2019.1649273	2019	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MiR-421 promotes the development of osteosarcoma by regulating MCPIP1 expression	https://doi.org/10.1080/15384047.2019.1683331	2019	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-340-5p suppresses osteosarcoma development by down-regulating the Wnt/?-catenin signaling pathway via targeting the STAT3 gene	https://doi.org/10.26355/eurrev_201902_16985	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MiR-564 is down-regulated in osteosarcoma and inhibits the proliferation of osteosarcoma cells via targeting Akt	https://doi.org/10.1016/j.gene.2017.12.028	2018	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-497 inhibits cell proliferation, migration, and invasion by targeting AMOT in human osteosarcoma cells	https://doi.org/10.2147/OTT.S95204	2016	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-192 inhibits the proliferation, migration and invasion of osteosarcoma cells and promotes apoptosis by targeting matrix metalloproteinase-11	https://doi.org/10.3892/ol.2018.8239	2018	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Inhibition of miR-664a interferes with the migration of osteosarcoma cells via modulation of MEG3	https://doi.org/10.1016/j.bbrc.2017.06.174	2017	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
LncRNA MEG3 negatively modified osteosarcoma development through regulation of miR-361-5p and FoxM1	https://doi.org/10.1002/jcp.28026	2019	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-217 regulates WASF3 expression and suppresses tumor growth and metastasis in osteosarcoma	https://doi.org/10.1371/journal.pone.0109138	2014	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-328-3p mediates the anti-tumor effect in osteosarcoma via directly targeting MMP-16	https://doi.org/10.1186/s12935-019-0829-7	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View

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