MicroRNA Childhood Cancer Catalog (M3Cs)

Publication Title	DOI	Year
MiR-22 is frequently downregulated in medulloblastomas and inhibits cell proliferation via the novel target PAPST1.	https://doi.org/10.1111/bpa.12136	2014	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Mir-34a mimics are potential therapeutic agents for p53-mutated and chemo-resistant brain tumour cells.	https://doi.org/10.1371/journal.pone.0108514	2014	Cell line 2 Master/Detail View	Cell line and drug 3 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-let-7f-1 regulates SPARC mediated cisplatin resistance in medulloblastoma cells.	https://doi.org/10.1016/j.cellsig.2014.06.014	2014	Cell line 0 Master/Detail View	Cell line and drug 2 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma.	https://doi.org/10.1007/s00401-012-0969-5	2012	Cell line 6 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA mediates DNA demethylation events triggered by retinoic acid during neuroblastoma cell differentiation	https://doi.org/10.1158/0008-5472.CAN-10-1534	2010	Cell line 1 Master/Detail View	Cell line and drug 4 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Regulation of Nuclear Receptor Nur77 by miR-124.	https://doi.org/10.1371/journal.pone.0148433	2016	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-149* induces apoptosis by inhibiting Akt1 and E2F1 in human cancer cells	https://doi.org/10.1002/mc.20647	2010	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 2 Master/Detail View
miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro	https://doi.org/10.1016/j.bbrc.2010.03.076	2010	Cell line 0 Master/Detail View	Cell line and drug 11 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro	https://doi.org10.1016/j.bbrc.2010.03.076	2010	Cell line 0 Master/Detail View	Cell line and drug 1 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-542-5p as a novel tumor suppressor in neuroblastoma	https://doi.org/10.1016/j.canlet.2011.01.016	2011	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 2 Master/Detail View
Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells	https://doi.org/10.1186/1471-2199-11-95	2010	Cell line 1 Master/Detail View	Cell line and drug 1 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation	https://doi.org/10.1093/nar/gkq604	2010	Cell line 0 Master/Detail View	Cell line and drug 2 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma	https://doi.org/10.1093/carcin/bgr073	2011	Cell line 6 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
LncRNA MALAT1 Promotes Cancer Metastasis in Osteosarcoma via Activation of the PI3K-Akt Signaling Pathway	https://doi.org/10.1159/000495550	2018	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MiR-542-5p is a negative prognostic factor and promotes osteosarcoma tumorigenesis by targeting HUWE1	https://doi.org/10.18632/oncotarget.6199	2015	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-142-5p suppresses proliferation and promotes apoptosis of human osteosarcoma cell line, HOS, by targeting PLA2G16 through the ERK1/2 signaling pathway	https://doi.org/10.3892/ol.2018.9712	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Long non-coding RNA ROR regulated ABCB1 to induce cisplatin resistance in osteosarcoma by sponging miR-153-3p	https://doi.org/10.26355/eurrev_201909_18828	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Gankyrin promotes osteosarcoma tumorigenesis by forming a positive feedback loop with YAP	https://doi.org/10.1016/j.cellsig.2019.109460	2020	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-130b-5p accelerates the migration and invasion of osteosarcoma via binding to TIMP2	https://doi.org/10.26355/eurrev_201911_19419	2019	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-503 acts as a tumor suppressor in osteosarcoma by targeting L1CAM	https://doi.org/10.1371/journal.pone.0114585	2014	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View

Publications