MicroRNA Childhood Cancer Catalog (M3Cs)

Publication Title	DOI	Year
Expression of miR-124 inhibits growth of medulloblastoma cells.	https://doi.org/10.1093/neuonc/nos281	2013	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets	https://doi.org/10.1128/MCB.01694-08	2009	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
microRNA-10b Is Overexpressed and Critical for Cell Survival and Proliferation in Medulloblastoma.	https://doi.org/10.1371/journal.pone.0137845	2015	Cell line 2 Master/Detail View	Cell line and drug 4 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Ligustrazine Inhibits Growth, Migration and Invasion of Medulloblastoma Daoy Cells by Up-Regulation of miR-211.	https://doi.org/10.1159/000493712	2018	Cell line 0 Master/Detail View	Cell line and drug 1 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
A statin-regulated microRNA represses human c-Myc expression and function.	https://doi.org/10.1002/emmm.201101045	2012	Cell line 0 Master/Detail View	Cell line and drug 1 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.	https://doi.org/10.1038/emboj.2008.172	2008	Cell line 6 Master/Detail View	Cell line and drug 6 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Effects of microRNA-494 on proliferation, migration, invasion, and apoptosis of medulloblastoma cells by mediating c-myc through the p38 MAPK signaling pathway	https://doi.org/10.1002/jcb.27559	2018	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MicroRNA-206 inhibits the viability and migration of medulloblastoma cells by targeting LIM and SH3 protein 1.	https://doi.org/10.3892/etm.2017.5016	2017	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-219 inhibits the proliferation, migration and invasion of medulloblastoma cells by targeting CD164.	https://doi.org/10.3892/ijmm.2014.1749	2014	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma.	https://doi.org/10.1093/neuonc/nos002	2012	Cell line 3 Master/Detail View	Cell line and drug 3 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells.	https://doi.org/10.1080/09168451.2018.1553604	2018	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene	https://doi.org/10.1158/1541-7786.MCR-07-2102	2008	Cell line 4 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM	https://doi.org/10.1371/journal.pone.0002236	2008	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
microRNA-144-3p suppresses human neuroblastoma cell proliferation by targeting HOXA7	https://doi.org/10.26355/eurrev_201901_16885	2019	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 1 Master/Detail View
MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2	https://doi.org/10.1038/cdd.2010.172	2011	Cell line 2 Master/Detail View	Cell line and drug 2 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 1 Master/Detail View
MicroRNA-31 suppresses medulloblastoma cell growth by inhibiting DNA replication through minichromosome maintenance 2.	https://doi.org/10.18632/oncotarget.2043	2014	Cell line 1 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-106b is overexpressed in medulloblastomas and interacts directly with PTEN.	https://doi.org/10.1111/nan.12169	2015	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
MiR-148a, a microRNA upregulated in the WNT subgroup tumors, inhibits invasion and tumorigenic potential of medulloblastoma cells by targeting Neuropilin 1.	https://doi.org/10.18632/oncoscience.137	2015	Cell line 3 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
miR-218 is downregulated and directly targets SH3GL1 in childhood medulloblastoma.	https://doi.org/10.3892/mmr.2013.1639	2013	Cell line 4 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View
Irradiation-induced angiogenesis is associated with an MMP-9-miR-494-syndecan-1 regulatory loop in medulloblastoma cells.	https://doi.org/10.1038/onc.2013.151	2013	Cell line 2 Master/Detail View	Cell line and drug 0 Master/Detail View	Clinical and drug 0 Master/Detail View	Clinical 0 Master/Detail View

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